A team of researchers from the University of Manchester have developed this new antimicrobial coating primarily for catheters. In its researched, the team investigated a number of positive-charge compounds identified to exert strong antimicrobial effects against organisms primarily responsible for hospital base, acquired urinary tract infection or UTI. From this investigation, they are able to develop a combination of new compounds that killed microorganisms such as E. coli of the family Enterobacteriaceae, a genus of aerobic gram-negative rod-shaped bacteria. An antimicrobial coating could also be used potentially for other medical implants, such as prosthetic devices and artificial heart valves, according to a press release from the Society for General Microbiology.
The primary purpose of this coating is to protect medical catheters from urinary tract microorganisms’ colonization or clumping together of bacteria to form biofilms which might create difficulties in clearing infections using antibiotics. In the study, it was found out that live organisms adhering to exposed surfaces had reduced to more than 90%. Such reduction is significant enough to interrupt the urinary tract infections by delaying the attachment of microorganism to the catheter surface; thereby lessening healthcare costs from hospital acquired infections and improved patient’s comfort.
Replacing catheters may solve the problems, but replacement is very costly and also time consuming.